(Public Summary)

Mandate

The MARA Rating Committee is responsible for determining and maintaining standardized market access risk ratings for pharmaceutical drug–indication pairs.

Its objective is to ensure consistency, comparability, and defensibility across assets and over time.

 

Composition

The committee consists of multidisciplinary experts with experience in health technology assessment, payer policy, health economics, clinical evaluation, and reimbursement decision processes.

Committee composition may rotate by therapeutic area.

 

Independence

  • No single analyst determines a rating outcome.

  • Ratings are determined through structured committee judgment.

  • Members with material conflicts of interest recuse themselves.

  • Evidence is restricted to public, verifiable sources.

  • Issuers may correct factual inaccuracies but cannot influence rating outcomes.

 

Decision Process

Each rating undergoes:

  1. Structured pre-read scoring across 10 domains

  2. Domain-level challenge and discussion

  3. Committee deliberation

  4. Formal vote

  5. Documentation of rationale and minutes

 

Surveillance Responsibilities

The committee oversees:

  • Event-driven reviews following material developments

  • Periodic review of outstanding ratings

  • Rating actions (Affirmed, Upgrade, Downgrade, Under Review, Watch Positive/Negative)

 

Records & Transparency

Committee minutes are documented internally.

Public methodology and surveillance policies are maintained and updated as required.